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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733374
Species: Homo sapiens
RGD Object: Gene
Symbol: ST14
Name: ST14 transmembrane serine protease matriptase
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ST14affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of ST14 promoterPMID:27901495
ST14decreases methylationEXP 6480464CTDBenzo(a)pyrene results in decreased methylation of ST14 exonPMID:27901495
ST14decreases expressionISOSt14 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of ST14 mRNAPMID:27195522
ST14decreases methylationISOSt14 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased methylation of ST14 intronPMID:27901495
ST14increases expressionISOSt14 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of ST14 mRNAPMID:19770486 PMID:21715664
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