Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731705
Species: Mus musculus
RGD Object: Gene
Symbol: Dnajc5
Name: DnaJ heat shock protein family (Hsp40) member C5
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dnajc5affects methylationISODNAJC5 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of DNAJC5 5' UTR; Benzo(a)pyrene affects the methylation of DNAJC5 intronPMID:27901495 PMID:30157460
Dnajc5decreases methylationISODNAJC5 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of DNAJC5 promoterPMID:27901495
Dnajc5increases mutagenesisISODNAJC5 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased mutagenesis of DNAJC5 genePMID:25435355
Go Back to source page   Continue to Ontology report