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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731009
Species: Mus musculus
RGD Object: Gene
Symbol: Tacr1
Name: tachykinin receptor 1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tacr1decreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of TACR1 mRNAPMID:15894712
Tacr1multiple interactionsEXP 6480464CTD[arsenite co-treated with Benzo(a)pyrene] results in decreased expression of TACR1 mRNAPMID:15894712
Tacr1affects methylationISOTACR1 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of TACR1 exonPMID:27901495
Tacr1decreases expressionISOTacr1 (Rattus norvegicus)6480464CTDBenzo(a)pyrene results in decreased expression of TACR1 mRNAPMID:21839799
Tacr1increases expressionISOTacr1 (Rattus norvegicus)6480464CTDBenzo(a)pyrene results in increased expression of TACR1 mRNAPMID:22374506
Tacr1increases methylationISOTACR1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of TACR1 3' UTRPMID:27901495
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