GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Akap12 | affects methylation | ISO | AKAP12 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of AKAP12 promoter | PMID:27901495 | Akap12 | decreases expression | ISO | Akap12 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of AKAP12 mRNA | PMID:19770486 | Akap12 | decreases methylation | ISO | AKAP12 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of AKAP12 exon | PMID:27901495 | Akap12 | increases expression | ISO | AKAP12 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of AKAP12 mRNA; Benzo(a)pyrene results in increased expression of AKAP12 protein | PMID:20106945 PMID:21632981 PMID:21871943 PMID:22316170 PMID:26238291 PMID:32234424 PMID:32717239 PMID:35870112 | Akap12 | increases expression | ISO | Akap12 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of AKAP12 mRNA | PMID:32417428 | Akap12 | increases methylation | ISO | Akap12 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of AKAP12 intron | PMID:27901495 | |
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