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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70552
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acsl3
Name: acyl-CoA synthetase long-chain family member 3
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acsl3decreases expressionISOACSL3 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of ACSL3 mRNAPMID:19221603 PMID:20064835 PMID:20106945 PMID:21632981
Acsl3decreases expressionISOAcsl3 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of ACSL3 mRNAPMID:19770486 PMID:22228805
Acsl3decreases methylationISOACSL3 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of ACSL3 3' UTRPMID:27901495
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