GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hif3a | affects methylation | ISO | HIF3A (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of HIF3A 3' UTR; Benzo(a)pyrene affects the methylation of HIF3A promoter | PMID:27901495 | Hif3a | decreases expression | ISO | HIF3A (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of HIF3A mRNA | PMID:21871943 | Hif3a | increases expression | ISO | Hif3a (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of HIF3A mRNA | PMID:22228805 PMID:27195522 | Hif3a | increases methylation | ISO | HIF3A (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of HIF3A 5' UTR | PMID:27901495 | |
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