GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ICAM1 | affects methylation | EXP | | 6480464 | CTD | Benzo(a)pyrene affects the methylation of ICAM1 promoter | PMID:27901495 | ICAM1 | increases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased expression of ICAM1 mRNA; Benzo(a)pyrene results in increased expression of ICAM1 protein | PMID:21632981 PMID:22313677 PMID:26238291 PMID:31748929 PMID:32234424 | ICAM1 | multiple interactions | EXP | | 6480464 | CTD | [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide co-treated with Benzo(a)pyrene] results in increased expression of ICAM1 protein; Benzo(a)pyrene affects the reaction [AHR protein affects the expression of ICAM1 protein] | PMID:31748929 | ICAM1 | increases expression | ISO | Icam1 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of ICAM1 mRNA | PMID:19770486 PMID:22228805 PMID:22610609 | |
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