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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69233
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Smpx
Name: small muscle protein, X-linked
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smpxaffects methylationISOSMPX (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of SMPX exonPMID:27901495
Smpxdecreases expressionISOSMPX (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of SMPX mRNAPMID:32234424
Smpxdecreases expressionISOSmpx (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of SMPX mRNAPMID:22228805
Smpxdecreases methylationISOSMPX (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of SMPX promoterPMID:27901495
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