GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Clu | decreases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of CLU mRNA | PMID:19770486 | Clu | increases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased expression of CLU mRNA | PMID:15034205 PMID:22228805 | Clu | multiple interactions | EXP | | 6480464 | CTD | AHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of CLU mRNA] | PMID:15034205 | Clu | affects methylation | ISO | CLU (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of CLU intron; Benzo(a)pyrene affects the methylation of CLU promoter | PMID:27901495 PMID:30157460 | |
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