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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628670
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppif
Name: peptidylprolyl isomerase F
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppifaffects methylationISOPPIF (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of PPIF promoterPMID:27901495
Ppifdecreases expressionISOPPIF (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of PPIF mRNAPMID:20106945
Ppifdecreases methylationISOPPIF (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of PPIF 3' UTRPMID:27901495
Ppifincreases expressionISOPpif (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of PPIF mRNAPMID:14625279
Ppifincreases expressionISOPPIF (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of PPIF mRNAPMID:20064835
Ppifmultiple interactionsISOPpif (Mus musculus)6480464CTD[Potassium Dichromate co-treated with potassium chromate(VI)] inhibits the reaction [Benzo(a)pyrene results in increased expression of PPIF mRNA]PMID:14625279
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