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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62254
Species: Mus musculus
RGD Object: Gene
Symbol: S1pr3
Name: sphingosine-1-phosphate receptor 3
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S1pr3affects methylationISOS1PR3 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of S1PR3 3' UTRPMID:30157460
S1pr3increases expressionISOS1PR3 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of S1PR3 mRNAPMID:20106945 PMID:32234424
S1pr3increases methylationISOS1PR3 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of S1PR3 3' UTRPMID:27901495
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