GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rapgef3 | affects methylation | ISO | RAPGEF3 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of RAPGEF3 exon | PMID:27901495 | Rapgef3 | decreases expression | ISO | RAPGEF3 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of RAPGEF3 mRNA | PMID:22316170 | Rapgef3 | increases expression | ISO | RAPGEF3 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of RAPGEF3 mRNA | PMID:32234424 | Rapgef3 | increases expression | ISO | Rapgef3 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of RAPGEF3 mRNA | PMID:32417428 | Rapgef3 | increases methylation | ISO | RAPGEF3 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of RAPGEF3 promoter | PMID:27901495 | Rapgef3 | increases response to substance | ISO | RAPGEF3 (Homo sapiens) | 6480464 | CTD | RAPGEF3 protein results in increased susceptibility to Benzo(a)pyrene | PMID:22167199 | Rapgef3 | multiple interactions | ISO | RAPGEF3 (Homo sapiens) | 6480464 | CTD | RAPGEF3 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium] | PMID:22167199 | |
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