Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62121
Species: Mus musculus
RGD Object: Gene
Symbol: Kcnab3
Name: potassium voltage-gated channel, shaker-related subfamily, beta member 3
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnab3multiple interactionsEXP 6480464CTDBenzo(a)pyrene promotes the reaction [AHR protein binds to KCNAB3 promoter]

PMID:19654925
Kcnab3decreases expressionISORGD:618306480464CTDBenzo(a)pyrene results in decreased expression of KCNAB3 mRNA

PMID:21839799
Kcnab3increases expressionISORGD:13507476480464CTDBenzo(a)pyrene results in increased expression of KCNAB3 mRNA

PMID:22316170
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.