GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cd14 | decreases expression | ISO | CD14 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of CD14 mRNA | PMID:20064835 | Cd14 | decreases methylation | ISO | CD14 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of CD14 3' UTR; Benzo(a)pyrene results in decreased methylation of CD14 exon | PMID:27901495 | Cd14 | increases expression | ISO | CD14 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of CD14 mRNA | PMID:20106945 | Cd14 | increases expression | ISO | Cd14 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene metabolite results in increased expression of CD14 mRNA; Benzo(a)pyrene results in increased expression of CD14 mRNA | PMID:19770486 PMID:32553695 | Cd14 | multiple interactions | ISO | CD14 (Homo sapiens) | 6480464 | CTD | [Benzo(a)pyrene co-treated with Calcitriol] results in increased expression of CD14 protein; Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of CD14 mRNA]; Benzo(a)pyrene promotes the reaction [Lithocholic Acid results in increased expression of CD14 mRNA] | PMID:19244278 PMID:29524502 | Cd14 | multiple interactions | ISO | Cd14 (Mus musculus) | 6480464 | CTD | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of CD14 mRNA] | PMID:22228805 | |
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