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RGD ID: 62050
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnni2
Name: troponin I2, fast skeletal type
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:13449786480464CTDBenzo(a)pyrene affects the expression of TNNI2 mRNA

decreases expressionISORGD:623426480464CTDBenzo(a)pyrene results in decreased expression of TNNI2 mRNA

PMID:22228805, PMID:23735875
increases expressionISORGD:13449786480464CTDBenzo(a)pyrene results in increased expression of TNNI2 mRNA

PMID:21632981, PMID:22316170
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.