GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Atp6ap1 | affects methylation | ISO | ATP6AP1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of ATP6AP1 promoter | PMID:27901495 PMID:30157460 | Atp6ap1 | decreases methylation | ISO | ATP6AP1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of ATP6AP1 3' UTR | PMID:27901495 | Atp6ap1 | increases expression | ISO | Atp6ap1 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of ATP6AP1 mRNA | PMID:22228805 | Atp6ap1 | increases methylation | ISO | ATP6AP1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of ATP6AP1 exon | PMID:27901495 | Atp6ap1 | multiple interactions | ISO | Atp6ap1 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene promotes the reaction [AHR protein binds to ATP6AP1 promoter] | PMID:19654925 | |
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