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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620239
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kif2c
Name: kinesin family member 2C
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kif2cdecreases expressionISOKIF2C (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of KIF2C mRNAPMID:20064835
Kif2cdecreases expressionISOKif2c (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of KIF2C mRNAPMID:19770486 PMID:22228805
Kif2cdecreases methylationISOKif2c (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased methylation of KIF2C exon; Benzo(a)pyrene results in decreased methylation of KIF2C intronPMID:27901495
Kif2cincreases expressionISOKif2c (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of KIF2C mRNAPMID:20713471 PMID:32417428
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