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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3140
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Myh9
Name: myosin, heavy chain 9
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Myh9decreases expressionISOMYH9 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of MYH9 mRNA; Benzo(a)pyrene results in decreased expression of MYH9 proteinPMID:20064835 PMID:32717239
Myh9decreases expressionISOMyh9 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of MYH9 mRNAPMID:19770486 PMID:25908611
Myh9increases expressionISOMyh9 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of MYH9 mRNAPMID:22228805 PMID:22610609
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