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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3101
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mobp
Name: myelin-associated oligodendrocyte basic protein
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mobpincreases expressionISORGD:7365746480464CTDBenzo(a)pyrene results in increased expression of MOBP mRNA

PMID:22316170
Mobpmultiple interactionsISORGD:109086480464CTDBenzo(a)pyrene promotes the reaction [AHR protein binds to MOBP promoter]

PMID:19654925
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.