An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID:
MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Benzo(a)pyrene results in increased expression of and results in increased activity of CASP3 protein; Catechin analog inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP3 mRNA]; Catechin analog inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP3 protein]; Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]
Benzo(a)pyrene results in decreased expression of CASP3 mRNA; Benzo(a)pyrene results in decreased expression of CASP3 protein; Benzo(a)pyrene results in decreased expression of CASP3 protein modified form
[Quercetin co-treated with Curcumin] inhibits the reaction [Benzo(a)pyrene results in decreased activity of CASP3 protein]; AHR protein inhibits the reaction [Benzo(a)pyrene results in decreased expression of CASP3 mRNA]; Benzo(a)pyrene results in decreased cleavage of and results in decreased activity of CASP3 protein; Chlordan promotes the reaction [Benzo(a)pyrene results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased activity of CASP3 protein]; Diosmin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]; GJA1 mutant form promotes the reaction [Benzo(a)pyrene results in increased activity of CASP3 protein]; Phytol inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP3 protein]; Plant Extracts inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [Benzo(a)pyrene results in decreased activity of CASP3 protein]; thymoquinone inhibits the reaction [Benzo(a)pyrene results in decreased expression of CASP3 protein]
2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]; [[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of CASP3 protein; AKT1 protein modified form inhibits the reaction [Wortmannin inhibits the reaction [[[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of CASP3 protein]]; Clotrimazole inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP3 mRNA]; CYP1B1 mutant form inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP3 mRNA]; Estradiol inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]; fostriecin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]]; MCL1 protein affects the reaction [[[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of CASP3 protein]; MCL1 protein inhibits the reaction [Sirolimus inhibits the reaction [[[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of CASP3 protein]]; MCL1 protein inhibits the reaction [Wortmannin inhibits the reaction [[[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of CASP3 protein]]; MCL1 protein promotes the reaction [[[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of CASP3 protein]; Nitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]; Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]]; Okadaic Acid inhibits the reaction [Estradiol inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]]; Okadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]]; Sirolimus inhibits the reaction [[[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of CASP3 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]; USP7 protein affects the reaction [[[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of CASP3 protein]; Wortmannin inhibits the reaction [[[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of CASP3 protein]
