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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2160
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Asgr1
Name: asialoglycoprotein receptor 1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Asgr1decreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of ASGR1 mRNAPMID:21839799
Asgr1affects methylationISOASGR1 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of ASGR1 promoterPMID:27901495
Asgr1decreases expressionISOASGR1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of ASGR1 mRNAPMID:32234424
Asgr1decreases methylationISOASGR1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of ASGR1 5' UTRPMID:27901495
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