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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1614254
Species: Mus musculus
RGD Object: Gene
Symbol: Hdac9
Name: histone deacetylase 9
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hdac9increases methylationEXP 6480464CTDBenzo(a)pyrene results in increased methylation of HDAC9 intronPMID:27901495
Hdac9affects methylationISOHDAC9 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of HDAC9 intron; Benzo(a)pyrene affects the methylation of HDAC9 promoterPMID:27901495 PMID:30157460
Hdac9increases expressionISOHDAC9 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of HDAC9 mRNAPMID:32234424
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