GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | FASLG | increases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased expression of FASLG mRNA; Benzo(a)pyrene results in increased expression of FASLG protein | PMID:16041517 PMID:18247414 | FASLG | multiple interactions | EXP | | 6480464 | CTD | AHR mutant form inhibits the reaction [Benzo(a)pyrene promotes the reaction [FASLG protein results in increased cleavage of CASP8 protein]]; AHR mutant form inhibits the reaction [Benzo(a)pyrene results in increased activity of [FASLG protein binds to FASLG protein]]; Benzo(a)pyrene promotes the reaction [FASLG protein results in increased cleavage of CASP8 protein]; Benzo(a)pyrene results in increased activity of [FASLG protein binds to FASLG protein]; Nitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of FASLG protein] | PMID:16041517 PMID:22951985 | | ||||||||||||||||||||||
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