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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1605126
Species: Homo sapiens
RGD Object: Gene
Symbol: EPHB2
Name: EPH receptor B2
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EPHB2affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of EPHB2 3' UTR; Benzo(a)pyrene affects the methylation of EPHB2 intronPMID:30157460
EPHB2increases mutagenesisEXP 6480464CTDBenzo(a)pyrene results in increased mutagenesis of EPHB2 genePMID:25435355
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