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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1598149
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vasn
Name: vasorin
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vasnaffects methylationISOVASN (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of VASN promoterPMID:27901495
Vasnincreases expressionISOVASN (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of VASN mRNAPMID:20064835
Vasnincreases methylationISOVASN (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of VASN 5' UTRPMID:27901495
Vasnmultiple interactionsISOVasn (Mus musculus)6480464CTDBenzo(a)pyrene promotes the reaction [AHR protein binds to VASN promoter]PMID:19654925
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