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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1595392
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rgmb
Name: repulsive guidance molecule BMP co-receptor b
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:16150866480464CTDBenzo(a)pyrene results in decreased expression of RGMB mRNA

PMID:22228805
increases expressionISORGD:13507256480464CTDBenzo(a)pyrene results in increased expression of RGMB mRNA

PMID:20106945, PMID:21632981, PMID:22316170, PMID:26238291
multiple interactionsISORGD:13507256480464CTD[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of RGMB mRNA

PMID:20146248
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