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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1594597
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atp8a2
Name: ATPase phospholipid transporting 8A2
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atp8a2affects methylationISOATP8A2 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of ATP8A2 3' UTR; Benzo(a)pyrene affects the methylation of ATP8A2 exon; Benzo(a)pyrene affects the methylation of ATP8A2 intronPMID:27901495 PMID:30157460
Atp8a2affects methylationISOAtp8a2 (Mus musculus)6480464CTDBenzo(a)pyrene affects the methylation of ATP8A2 intronPMID:27901495
Atp8a2increases methylationISOATP8A2 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of ATP8A2 exonPMID:27901495
Atp8a2increases methylationISOAtp8a2 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased methylation of ATP8A2 exonPMID:27901495
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