GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pin4 | affects methylation | ISO | PIN4 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of PIN4 promoter | PMID:27901495 | Pin4 | decreases expression | ISO | PIN4 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of PIN4 protein | PMID:33278487 | Pin4 | increases expression | ISO | Pin4 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of PIN4 mRNA | PMID:15034205 PMID:19770486 | Pin4 | increases methylation | ISO | PIN4 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of PIN4 5' UTR | PMID:27901495 | Pin4 | multiple interactions | ISO | Pin4 (Mus musculus) | 6480464 | CTD | AHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of PIN4 mRNA] | PMID:15034205 | |
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