GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rprml | decreases expression | ISO | Rprml (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of RPRML mRNA | PMID:21569818 PMID:27195522 | Rprml | decreases methylation | ISO | RPRML (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of RPRML promoter | PMID:27901495 | Rprml | increases methylation | ISO | RPRML (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of RPRML 3' UTR; Benzo(a)pyrene results in increased methylation of RPRML exon | PMID:27901495 | |
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