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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558559
Species: Mus musculus
RGD Object: Gene
Symbol: Clec7a
Name: C-type lectin domain family 7, member a
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Clec7adecreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of CLEC7A mRNAPMID:21569818
Clec7aincreases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of CLEC7A mRNAPMID:20504355 PMID:22228805
Clec7aincreases methylationISOCLEC7A (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of CLEC7A exonPMID:27901495
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