GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CLDN2 | affects methylation | EXP | | 6480464 | CTD | Benzo(a)pyrene affects the methylation of CLDN2 5' UTR; Benzo(a)pyrene affects the methylation of CLDN2 promoter | PMID:27901495 | CLDN2 | increases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased expression of CLDN2 mRNA | PMID:32234424 | CLDN2 | increases methylation | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of CLDN2 3' UTR | PMID:27901495 | CLDN2 | increases expression | ISO | Cldn2 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of CLDN2 mRNA | PMID:19770486 PMID:27195522 | CLDN2 | multiple interactions | ISO | Cldn2 (Mus musculus) | 6480464 | CTD | [Benzo(a)pyrene co-treated with Dextran Sulfate] results in decreased expression of CLDN2 mRNA | PMID:26271895 | |
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