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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350576
Species: Homo sapiens
RGD Object: Gene
Symbol: FAM53B
Name: family with sequence similarity 53 member B
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FAM53Bdecreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of FAM53B mRNAPMID:20064835
FAM53Bdecreases methylationEXP 6480464CTDBenzo(a)pyrene results in decreased methylation of FAM53B 3' UTR; Benzo(a)pyrene results in decreased methylation of FAM53B 5' UTR; Benzo(a)pyrene results in decreased methylation of FAM53B promoterPMID:27901495
FAM53Bincreases expressionISOFam53b (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of FAM53B mRNAPMID:19770486 PMID:22610609
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