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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347443
Species: Homo sapiens
RGD Object: Gene
Symbol: STRA6
Name: signaling receptor and transporter of retinol STRA6
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
STRA6affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of STRA6 5' UTR; Benzo(a)pyrene affects the methylation of STRA6 promoterPMID:27901495
STRA6decreases methylationEXP 6480464CTDBenzo(a)pyrene results in decreased methylation of STRA6 3' UTRPMID:27901495
STRA6affects expressionISOStra6 (Mus musculus)6480464CTDBenzo(a)pyrene affects the expression of STRA6 mRNAPMID:22342234
STRA6increases expressionISOStra6 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of STRA6 mRNAPMID:27195522
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