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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1343139
Species: Homo sapiens
RGD Object: Gene
Symbol: SH3GL2
Name: SH3 domain containing GRB2 like 2, endophilin A1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SH3GL2affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of SH3GL2 promoterPMID:27901495
SH3GL2decreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of SH3GL2 mRNAPMID:20106945
SH3GL2decreases expressionISOSh3gl2 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of SH3GL2 mRNAPMID:22228805
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