GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | RAPGEF5 | affects expression | EXP | | 6480464 | CTD | Benzo(a)pyrene affects the expression of RAPGEF5 mRNA | PMID:21632981 | RAPGEF5 | affects methylation | EXP | | 6480464 | CTD | Benzo(a)pyrene affects the methylation of RAPGEF5 5' UTR; Benzo(a)pyrene affects the methylation of RAPGEF5 intron; Benzo(a)pyrene affects the methylation of RAPGEF5 promoter | PMID:27901495 PMID:30157460 | RAPGEF5 | decreases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of RAPGEF5 mRNA | PMID:20106945 | RAPGEF5 | increases expression | ISO | Rapgef5 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of RAPGEF5 mRNA | PMID:21964900 PMID:22228805 PMID:22610609 | RAPGEF5 | increases expression | ISO | Rapgef5 (Rattus norvegicus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of RAPGEF5 mRNA | PMID:21839799 | |
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