GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ASPH | increases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased expression of ASPH mRNA | PMID:21871943 PMID:26238291 | ASPH | increases methylation | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of ASPH promoter | PMID:27901495 | ASPH | increases mutagenesis | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased mutagenesis of ASPH gene | PMID:25435355 | ASPH | affects methylation | ISO | Asph (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of ASPH intron | PMID:27901495 | ASPH | decreases expression | ISO | Asph (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of ASPH mRNA | PMID:19770486 PMID:22228805 | ASPH | increases expression | ISO | Asph (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of ASPH mRNA | PMID:22228805 | ASPH | multiple interactions | ISO | Asph (Mus musculus) | 6480464 | CTD | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ASPH mRNA; AHR protein affects the reaction [Benzo(a)pyrene affects the expression of ASPH mRNA] | PMID:22228805 PMID:27858113 | |
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