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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1323267
Species: Homo sapiens
RGD Object: Gene
Symbol: RHOBTB3
Name: Rho related BTB domain containing 3
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RHOBTB3affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of RHOBTB3 intronPMID:30157460
RHOBTB3increases methylationEXP 6480464CTDBenzo(a)pyrene results in increased methylation of RHOBTB3 3' UTRPMID:27901495
RHOBTB3increases mutagenesisEXP 6480464CTDBenzo(a)pyrene results in increased mutagenesis of RHOBTB3 genePMID:25435355
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