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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1322055
Species: Mus musculus
RGD Object: Gene
Symbol: Man1a
Name: mannosidase 1, alpha
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Man1adecreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of MAN1A mRNAPMID:15034205
Man1adecreases methylationEXP 6480464CTDBenzo(a)pyrene results in decreased methylation of MAN1A intronPMID:27901495
Man1amultiple interactionsEXP 6480464CTDAHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of MAN1A mRNA]PMID:15034205
Man1adecreases expressionISOMAN1A1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of MAN1A1 mRNAPMID:32234424
Man1aincreases methylationISOMAN1A1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of MAN1A1 promoterPMID:27901495
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