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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319016
Species: Mus musculus
RGD Object: Gene
Symbol: Rgl1
Name: ral guanine nucleotide dissociation stimulator,-like 1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rgl1affects expressionEXP 6480464CTDBenzo(a)pyrene affects the expression of RGL1 mRNA

PMID:22342234
Rgl1increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of RGL1 mRNA

PMID:20713471, PMID:22228805
Rgl1affects methylationISORGD:13190156480464CTDBenzo(a)pyrene affects the methylation of RGL1 intron

PMID:30157460
Rgl1decreases expressionISORGD:13190156480464CTDBenzo(a)pyrene results in decreased expression of RGL1 mRNA

PMID:20064835
Rgl1increases expressionISORGD:13190156480464CTDBenzo(a)pyrene results in increased expression of RGL1 mRNA

PMID:21632981
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.