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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313349
Species: Mus musculus
RGD Object: Gene
Symbol: Hs2st1
Name: heparan sulfate 2-O-sulfotransferase 1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hs2st1decreases methylationEXP 6480464CTDBenzo(a)pyrene results in decreased methylation of HS2ST1 intronPMID:27901495
Hs2st1decreases expressionISOHS2ST1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of HS2ST1 mRNAPMID:20064835 PMID:20106945 PMID:21632981
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