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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313158
Species: Homo sapiens
RGD Object: Gene
Symbol: PLEKHA3
Name: pleckstrin homology domain containing A3
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PLEKHA3increases expressionISORGD:13131596480464CTDBenzo(a)pyrene results in increased expression of PLEKHA3 mRNA

PMID:15034205, PMID:22228805
PLEKHA3multiple interactionsISORGD:13131596480464CTDAHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of PLEKHA3 mRNA]

PMID:15034205
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.