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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312798
Species: Mus musculus
RGD Object: Gene
Symbol: Wnt9a
Name: wingless-type MMTV integration site family, member 9A
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Wnt9aincreases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of WNT9A mRNAPMID:19770486
Wnt9amultiple interactionsEXP 6480464CTDBenzo(a)pyrene affects the reaction [AHR protein binds to WNT9A promoter]PMID:19654925
Wnt9aaffects methylationISOWNT9A (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of WNT9A intronPMID:30157460
Wnt9aincreases methylationISOWNT9A (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of WNT9A 3' UTR; Benzo(a)pyrene results in increased methylation of WNT9A promoterPMID:27901495
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