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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312785
Species: Homo sapiens
RGD Object: Gene
Symbol: H2BC10
Name: H2B clustered histone 10
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H2BC10decreases methylationEXP 6480464CTDBenzo(a)pyrene results in decreased methylation of H2BC10 3' UTR; Benzo(a)pyrene results in decreased methylation of H2BC10 exon; Benzo(a)pyrene results in decreased methylation of H2BC10 promoterPMID:27901495
H2BC10increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of H2BC10 mRNAPMID:20106945
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