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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311711
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itga11
Name: integrin subunit alpha 11
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itga11decreases methylationISOITGA11 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of ITGA11 3' UTRPMID:27901495
Itga11increases expressionISOITGA11 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of ITGA11 mRNAPMID:22316170
Itga11increases methylationISOITGA11 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of ITGA11 promoterPMID:27901495
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