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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311100
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc51a
Name: solute carrier family 51 member A
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc51adecreases expressionISOSLC51A (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of SLC51A mRNAPMID:32234424
Slc51adecreases methylationISOSLC51A (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of SLC51A exon; Benzo(a)pyrene results in decreased methylation of SLC51A promoterPMID:27901495
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