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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310756
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Zfp541
Name: zinc finger protein 541
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Zfp541decreases expressionISOZNF541 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of ZNF541 mRNAPMID:32234424
Zfp541decreases methylationISOZNF541 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of ZNF541 promoterPMID:27901495
Zfp541increases mutagenesisISOZNF541 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased mutagenesis of ZNF541 genePMID:25435355
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