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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310680
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tmem151a
Name: transmembrane protein 151A
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tmem151adecreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of TMEM151A mRNAPMID:21839799
Tmem151aincreases expressionISOTMEM151A (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of TMEM151A mRNAPMID:32234424
Tmem151aincreases methylationISOTMEM151A (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of TMEM151A promoterPMID:27901495
Tmem151aincreases mutagenesisISOTMEM151A (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased mutagenesis of TMEM151A genePMID:25435355
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