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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308176
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccnb2
Name: cyclin B2
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnb2decreases expressionISOCCNB2 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of CCNB2 mRNAPMID:20064835 PMID:21632981 PMID:22316170 PMID:26238291
Ccnb2decreases expressionISOCcnb2 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of CCNB2 mRNAPMID:17942131 PMID:19770486 PMID:20504355
Ccnb2increases expressionISOCcnb2 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of CCNB2 mRNAPMID:21964900 PMID:22610609 PMID:32417428
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