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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307747
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Actl6a
Name: actin-like 6A
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Actl6adecreases expressionISOACTL6A (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of ACTL6A mRNAPMID:21632981
Actl6aincreases expressionISOActl6a (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of ACTL6A mRNAPMID:20504355 PMID:22228805
Actl6aincreases expressionISOACTL6A (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of ACTL6A proteinPMID:33278487
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