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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306741
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Clmn
Name: calmin
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Clmnaffects methylationISOCLMN (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of CLMN intron; Benzo(a)pyrene affects the methylation of CLMN promoterPMID:27901495 PMID:30157460
Clmndecreases expressionISOCLMN (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of CLMN mRNAPMID:20064835 PMID:32234424
Clmndecreases expressionISOClmn (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of CLMN mRNAPMID:22228805
Clmndecreases methylationISOCLMN (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of CLMN 3' UTRPMID:27901495
Clmnincreases expressionISOCLMN (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of CLMN mRNAPMID:22316170
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